
Transform simple low-carb tortillas into irresistible pizza roll-ups that satisfy cravings while keeping carbs in check. Each roll-up combines melted cheese, savory pepperoni, and Italian seasonings, creating the perfect handheld pizza experience without the guilt. The crispy exterior gives way to a gooey, flavorful center that makes every bite memorable.
Through countless family movie nights, these roll-ups have become our go-to snack. My teenagers now prefer these to regular pizza, often assembling their own with personalized toppings.
Low-Carb Ingredient Essentials
- Low-Carb Tortillas: Fresh and pliable tortillas make rolling easy and hold their shape perfectly.
- Mozzarella Cheese: Whole milk mozzarella ensures a creamy texture and melts beautifully.
- Premium Pepperoni: Thinly sliced pepperoni creates ideal layers and enhances the flavor.
- Italian Seasoning: A fresh blend of oregano, basil, and thyme brings authentic pizza flavor.
- Marinara Sauce: Choose a sugar-free marinara to keep the dish low-carb without sacrificing taste.
- Garlic Powder: Use high-quality garlic powder for consistent and even seasoning.
Creating Roll-Up Excellence
- Foundation Preparation:
- Bring tortillas to room temperature for maximum pliability. Layout workspace with ingredients easily accessible. Preheat oven to exactly 400°F, allowing the full preheat cycle to complete.
- Strategic Assembly:
- Place tortilla on a clean surface, sprinkling cheese evenly to the edges. Layer pepperoni in an overlapping pattern, leaving a half-inch border. Season thoroughly with the spice mixture.
- Rolling Technique:
- Start from one edge, rolling tightly while maintaining even pressure. Tuck filling as you roll to prevent spillage. Place seam-side down on a prepared baking sheet.
- Temperature Control:
- Position the rack in the center of the oven. Monitor during baking to prevent cheese overflow. Look for golden-brown spots and melted cheese as doneness indicators.
- Final Presentation:
- Allow rolls to rest for exactly 3 minutes before slicing. Cut at a slight angle for attractive presentation.

Through extensive testing, I've discovered that slightly chilling the pepperoni prevents oil release during baking. One memorable game day party taught me that pre-measuring ingredients for each roll ensures consistent results.
Perfect Presentation Strategy
Arrange golden slices upright on a serving platter, showcasing the spiral pattern. Provide warm marinara in small, individual dipping bowls. Garnish with fresh basil and a light dusting of grated Parmesan for added appeal.
Creative Variations
Transform the basic recipe by experimenting with different fillings—try Italian sausage and mushrooms or spinach and feta for a Greek-style twist. Create a buffalo chicken version using shredded chicken and hot sauce. Consider breakfast rolls with scrambled eggs and bacon.
Storage Success
Store uncooked rolls wrapped individually in plastic, refrigerating for up to 24 hours. Once baked, keep at room temperature for up to 2 hours. Reheat in a 350°F oven for 5 minutes to restore crispiness.

After perfecting these roll-ups through countless iterations, they've become more than just a low-carb alternative—they're a family favorite that happens to be healthy. The way they combine familiar pizza flavors in a convenient form makes them perfect for any occasion, from quick snacks to elegant appetizers. Whether served at a casual gathering or packed for lunch, these roll-ups prove that eating low-carb doesn't mean sacrificing flavor or satisfaction.
Frequently Asked Questions
- → Can I make these pizza roll ups ahead of time?
- Yes, you can assemble them ahead and store in the refrigerator for up to 24 hours before baking. They may need an extra minute or two of baking time if chilled.
- → What other toppings can I use?
- Try Italian sausage, ham, bell peppers, mushrooms, or olives. Just make sure any vegetables are finely chopped to roll easily.
- → How do I prevent the roll ups from unraveling?
- Place them seam-side down on the baking sheet, and the melted cheese will help hold them together while baking.
- → Can I freeze these roll ups?
- Yes, you can freeze them before baking. Wrap individually and freeze for up to 3 months. Thaw before baking.
- → What's the best way to reheat leftovers?
- Reheat in the oven at 350°F for 5-7 minutes or in an air fryer for 2-3 minutes to maintain crispiness.